Chemicals and Fertilizers Boards / Undertakings / PSU Closing in 0 days TDR #28521701

Rate Contract For Carrying Out Toxicological Studies From Good Laboratory Practice ( Glp ) Certified Laboratories Of Nano-Fertilizer Developed By R And D ( Bioagro ) Department , Rcf .

Issued by Boards / Undertakings / PSU · RCF TROMBAY UNIT, Maharashtra
Tender Value
Ref. Documents
Estimated cost
Bid Submission
09 Aug 2021
0 days left
EMD
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Bank guarantee accepted
Document Fee
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Non-refundable
Tender Type
Online

Tender Overview

Competition Type
NCB
Bidding Type
Tender
Location / State
RCF TROMBAY UNIT → Maharashtra
EMD Exemption
Not Available
Quantity
Not Available

Project Description

Rate Contract For Carrying Out Toxicological Studies From Good Laboratory Practice ( Glp ) Certified Laboratories Of Nano-Fertilizer Developed By R And D ( Bioagro ) Department , Rcf . - Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) : Iata For Skin Corrosion And Irritation ( Env / Jm / Mono ( 2014 ) 19 ) 2 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 428 - Skin Absorption: In Vitro Method 3 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 431 - In Vitro Skin Corrosion: Reconstructed Human Epidermis ( Rhe ) Test Method 4 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 437 - Bovine Corneal Opacity And Permeability Test Method For Evaluation Of Chemicals Likely To Cause Serious Eye Damage 5 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 433 – Acute Inhalation Toxicity For Evaluation Of Health Hazard From Short-Term Exposure To A Test Chemical By Inhalation. 6 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd 436 - Acute Inhalation Toxicity: Acute Toxic Class Method 7 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 473 - In Vitro Mammalian Chromosomal Aberration Test 8 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 476 - In Vitro Mammalian Cell Gene Mutation Tests Using The Hprt And Xprt Genes 9 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 487 - In Vitro Mammalian Cell Micronucleus Test 10 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Atp Cell Titer-Glo, Neutral Red Uptake, Ldh Release, Mtt, Xtt, Cell Impedance, Trypan Blue, Brdu, Alamar Blue, Wst-1, Live / Dead Cell Counting, Colony-Forming Efficiency 11 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) : In Addition, Test No. 489 - In Vitro Mammalian Alkaline Comet Assay For Measuring Dna Strand Breaks In Eukaryotic Cells May Also Be Included In The Test Panel. 12 Environmental Safety:Oecd Tg 201 - Aquatic Test: Fresh Water Algae, Cyanobacteria And Growth Inhibition Test 13 Environmental Safety:Oecd Tg 202 - Daphnia Sp. Acute Immobilization Test 14 Environmental Safety:Oecd Tg 203 - Fish Acute Toxicity Test 15 Environmental Safety:Oecd Tg 211 - Daphnia Magna Reproduction Test 16 Environmental Safety:Oecd Tg 236 - Fish Embryo Acute Toxicity Test On Embryonic Stages Of Fish ( Daniorerio ) . 17 Environmental Safety:Oecd Tg 208 - Terrestrial Plant Test: Seedling Emergence And Seedling Growth Test U.S. Environmental Protection Agency ( Us Epa ) - Six Bioassays: Allium And Vicia Root Tip Chromosome Breaks, Tradescantia Chromosome Break, Tradescantia Micronucleus, Tradescantia Stamen-Hair Mutation, And Arabidopsis Mutation Bioassays - For Detecting The Genotoxicity Of Environmental Agents ( Ma Et Al., 2005 ) . 18 Effects On Soil Microbiota And Macrobiota:Oecd Tg 222 – Earthworm Reproduction Test For Assessing The Effects Of Chemicals In Soil On The Reproductive Output ( And Other Sub-Lethal End Points ) Of The Earthworm Species Eisenia Fetida Or Eisenia Andrei 19 Effects On Soil Microbiota And Macrobiota:Oecd Tg 216 - For The Long-Term Effects After A Single Exposure Of Chemicals, On Nitrogen Transformation Activity Of Soil Microbiota 20 Effects On Soil Microbiota And Macrobiota:Oecd 217 – To Investigate Long-Term Effects After A Single Exposure Of Agrochemicals / Nonagrochemicals On Carbon Transformation Activity Of Soil Microorganisms 21 Effects On Soil Microbiota And Macrobiota:Oecd Tg 471 - Bacterial Reverse Mutation Test. Additionally, Clinical And Laboratory Standards Institute, Methods 02, 07, And 11 May Be Adopted For In Vitro Evaluation Of Antimicrobial Susceptibility Of Naps And Naips. Suitable Standard Guidelines To Evaluate Risk To Macrobiota May Also Be Developed And Provided By Regulators. Suitable Evaluation Method May Be Included To Assess Effect Of Naips On The Alteration Of Biotic And Abiotic Soil Properties. The Outcome Of Toxicity Tests May Be Used To Establish Thresholds Or Safe Levels Of Chemicals In Soil. Methods For Estimation Of The Half-Life Of The Nms In Soil May Also Be Included To Predict ( Potential ) Risk. 22 Effects On Soil Microbiota And Macrobiota:Oecd Tg 307 May Be Adopted With Necessary Adaptations For Aerobic-Anaerobic Transformation Of Naips Or Naps In Soil. 23 Effects On Soil Microbiota And Macrobiota:Oecd Guidelines For The Testing Of Chemicals, Section 3: Test No. 318 May Be Adopted With Modifications For Naips And Naps. 24 Packaging Compatibility Data: Decision Framework ( Oecd, Env / Jm / Mono ( 2019 ) 12 ) For Inclusion Of Physico-Chemical Parameters For Exposure And Fate Assessment Of Naips. 25 Packaging Compatibility Data:Avain Dietary Toxicity ( Oecd205 ) -5 Crop Samples 26 Packaging Compatibility Data:28-Day Repeated Dose Toxicity ( Oecd407 ) -5Crop Samples 27 Packaging Compatibility Data:Leaching Study ( Oecd 312 ) -3 Type Soil And One Plant 28 Packaging Compatibility Data:Nutritional Analysis-5 Crop Samples

Corrigendum

Sr No Corrigendum Date Corrigendum Type New Submission Date
1 27-Jul-2021 Bid submission date extension Date 04-Aug-2021
2 04-Aug-2021 CORR-II Bid submission date extension Date 09-Aug-2021

BOQ

Name of Work: Rate contract for Analysis /testing of Toxicological studies of Nano-fertilizer developed by RCF R and D (BioAgro) department from Good Laboratory Practice (GLP) certified laboratories
Sl.No.Item DescriptionItem Code / MakeQuantity /FrequencyUnits
11Human health safety (ENV/JM/MONO (2018) 4): IATA for skin corrosion and irritation (ENV/JM/MONO (2014) 19)1Per Test
22Human health safety (ENV/JM/MONO (2018) 4):OECD TG 428 - Skin absorption: In vitro method1Per Test
33Human health safety (ENV/JM/MONO (2018) 4):OECD TG 431 - In vitro skin corrosion: Reconstructed human epidermis (RHE) test method1Per Test
44Human health safety (ENV/JM/MONO (2018) 4):OECD TG 437 - Bovine corneal opacity and permeability test method for evaluation of chemicals likely to cause serious eye damage1Per Test
55Human health safety (ENV/JM/MONO (2018) 4):OECD TG 433 – Acute inhalation toxicity for evaluation of health hazard from short-term exposure to a test chemical by inhalation.1Per Test
66Human health safety (ENV/JM/MONO (2018) 4):OECD 436 - Acute inhalation toxicity: acute toxic class method1Per Test
77Human health safety (ENV/JM/MONO (2018) 4):OECD TG 473 - In vitro mammalian chromosomal aberration test1Per Test
88Human health safety (ENV/JM/MONO (2018) 4):OECD TG 476 - In vitro mammalian cell gene mutation tests using the HPRT and XPRT genes1Per Test
99Human health safety (ENV/JM/MONO (2018) 4):OECD TG 487 - In vitro mammalian cell micronucleus test1Per Test
1010Human health safety (ENV/JM/MONO (2018) 4):ATP Cell Titer-Glo, neutral red uptake, LDH release, MTT, XTT, cell impedance, trypan blue, BrdU, Alamar Blue, WST-1, live/dead cell counting, colony-forming efficiency1Per Test
1111Human health safety (ENV/JM/MONO (2018) 4): In addition, Test No. 489 - In vitro mammalian alkaline comet assay for measuring DNA strand breaks in eukaryotic cells may also be included in the test panel.1Per Test
1212Environmental safety:OECD TG 201 - Aquatic test: fresh water algae, cyanobacteria and growth inhibition test1Per Test
1313Environmental safety:OECD TG 202 - Daphnia sp. acute immobilization test1Per Test
1414Environmental safety:OECD TG 203 - Fish acute toxicity test1Per Test
1515Environmental safety:OECD TG 211 - Daphnia magna reproduction test1Per Test
1616Environmental safety:OECD TG 236 - Fish embryo acute toxicity test on embryonic stages of fish (Daniorerio).1Per Test
1717Environmental safety:OECD TG 208 - Terrestrial plant test: seedling emergence and seedling growth test U.S. Environmental Protection Agency (US EPA) - Six bioassays: Allium and Vicia root tip chromosome breaks, Tradescantia chromosome break, Tradescantia micronucleus, Tradescantia stamen-hair mutation, and Arabidopsis mutation bioassays - for detecting the genotoxicity of environmental agents (Ma et al., 2005).1Per Test
1818Effects on soil microbiota and macrobiota:OECD TG 222 – Earthworm reproduction test for assessing the effects of chemicals in soil on the reproductive output (and other sub-lethal end points) of the earthworm species Eisenia fetida or Eisenia andrei1Per Test
1919Effects on soil microbiota and macrobiota:OECD TG 216 - for the long-term effects after a single exposure of chemicals, on nitrogen transformation activity of soil microbiota1Per Test
2020Effects on soil microbiota and macrobiota:OECD 217 – to investigate long-term effects after a single exposure of agrochemicals/ nonagrochemicals on carbon transformation activity of soil microorganisms1Per Test
2121Effects on soil microbiota and macrobiota:OECD TG 471 - Bacterial Reverse Mutation Test. Additionally, Clinical and Laboratory Standards Institute, methods 02, 07, and 11 may be adopted for in vitro evaluation of antimicrobial susceptibility of NAPs and NAIPs. Suitable standard guidelines to evaluate risk to macrobiota may also be developed and provided by regulators. Suitable evaluation method may be included to assess effect of NAIPs on the alteration of biotic and abiotic soil properties. The outcome of toxicity tests may be used to establish thresholds or safe levels of chemicals in soil. Methods for estimation of the half-life of the NMs in soil may also be included to predict (potential) risk.1Per Test
2222Effects on soil microbiota and macrobiota:OECD TG 307 may be adopted with necessary adaptations for aerobic-anaerobic transformation of NAIPs or NAPs in soil.1Per Test
2323Effects on soil microbiota and macrobiota:OECD guidelines for the testing of chemicals, Section 3: Test No. 318 may be adopted with modifications for NAIPs and NAPs.1Per Test
2424Packaging compatibility data: Decision framework (OECD, ENV/JM/MONO (2019)12) for inclusion of physico-chemical parameters for exposure and fate assessment of NAIPs.1Per Test
2525Packaging compatibility data:Avain dietary toxicity(OECD205)-5 crop samples5Per crop
2626Packaging compatibility data:28-day repeated dose toxicity(OECD407)-5crop samples5Per Crop
2727Packaging compatibility data:Leaching study (OECD 312)-3 type soil and one plant1Per Test
2828Packaging compatibility data:Nutritional analysis-5 crop samples5Per Crop

AI Tender Summary

OUR REF NO 28521701
AUTHORITY Boards / Undertakings / PSU
TENDER VALUE Ref. Documents
LAST DATE 09-08-2021
Authority
Authority Name Rashtriya Chemicals And Fertilizers Limited
Work Description Rate Contract For Carrying Out Toxicological Studies From Good Laboratory Practice ( Glp ) Certified Laboratories Of Nano-Fertilizer Developed By R And D ( Bioagro ) Department , Rcf . - Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) : Iata For Skin Corrosion And Irritation ( Env / Jm / Mono ( 2014 ) 19 ) 2 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 428 - Skin Absorption: In Vitro Method 3 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 431 - In Vitro Skin Corrosion: Reconstructed Human Epidermis ( Rhe ) Test Method 4 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 437 - Bovine Corneal Opacity And Permeability Test Method For Evaluation Of Chemicals Likely To Cause Serious Eye Damage 5 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 433 – Acute Inhalation Toxicity For Evaluation Of Health Hazard From Short-Term Exposure To A Test Chemical By Inhalation. 6 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd 436 - Acute Inhalation Toxicity: Acute Toxic Class Method 7 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 473 - In Vitro Mammalian Chromosomal Aberration Test 8 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 476 - In Vitro Mammalian Cell Gene Mutation Tests Using The Hprt And Xprt Genes 9 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Oecd Tg 487 - In Vitro Mammalian Cell Micronucleus Test 10 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) :Atp Cell Titer-Glo, Neutral Red Uptake, Ldh Release, Mtt, Xtt, Cell Impedance, Trypan Blue, Brdu, Alamar Blue, Wst-1, Live / Dead Cell Counting, Colony-Forming Efficiency 11 Human Health Safety ( Env / Jm / Mono ( 2018 ) 4 ) : In Addition, Test No. 489 - In Vitro Mammalian Alkaline Comet Assay For Measuring Dna Strand Breaks In Eukaryotic Cells May Also Be Included In The Test Panel. 12 Environmental Safety:Oecd Tg 201 - Aquatic Test: Fresh Water Algae, Cyanobacteria And Growth Inhibition Test 13 Environmental Safety:Oecd Tg 202 - Daphnia Sp. Acute Immobilization Test 14 Environmental Safety:Oecd Tg 203 - Fish Acute Toxicity Test 15 Environmental Safety:Oecd Tg 211 - Daphnia Magna Reproduction Test 16 Environmental Safety:Oecd Tg 236 - Fish Embryo Acute Toxicity Test On Embryonic Stages Of Fish ( Daniorerio ) . 17 Environmental Safety:Oecd Tg 208 - Terrestrial Plant Test: Seedling Emergence And Seedling Growth Test U.S. Environmental Protection Agency ( Us Epa ) - Six Bioassays: Allium And Vicia Root Tip Chromosome Breaks, Tradescantia Chromosome Break, Tradescantia Micronucleus, Tradescantia Stamen-Hair Mutation, And Arabidopsis Mutation Bioassays - For Detecting The Genotoxicity Of Environmental Agents ( Ma Et Al., 2005 ) . 18 Effects On Soil Microbiota And Macrobiota:Oecd Tg 222 – Earthworm Reproduction Test For Assessing The Effects Of Chemicals In Soil On The Reproductive Output ( And Other Sub-Lethal End Points ) Of The Earthworm Species Eisenia Fetida Or Eisenia Andrei 19 Effects On Soil Microbiota And Macrobiota:Oecd Tg 216 - For The Long-Term Effects After A Single Exposure Of Chemicals, On Nitrogen Transformation Activity Of Soil Microbiota 20 Effects On Soil Microbiota And Macrobiota:Oecd 217 – To Investigate Long-Term Effects After A Single Exposure Of Agrochemicals / Nonagrochemicals On Carbon Transformation Activity Of Soil Microorganisms 21 Effects On Soil Microbiota And Macrobiota:Oecd Tg 471 - Bacterial Reverse Mutation Test. Additionally, Clinical And Laboratory Standards Institute, Methods 02, 07, And 11 May Be Adopted For In Vitro Evaluation Of Antimicrobial Susceptibility Of Naps And Naips. Suitable Standard Guidelines To Evaluate Risk To Macrobiota May Also Be Developed And Provided By Regulators. Suitable Evaluation Method May Be Included To Assess Effect Of Naips On The Alteration Of Biotic And Abiotic Soil Properties. The Outcome Of Toxicity Tests May Be Used To Establish Thresholds Or Safe Levels Of Chemicals In Soil. Methods For Estimation Of The Half-Life Of The Nms In Soil May Also Be Included To Predict ( Potential ) Risk. 22 Effects On Soil Microbiota And Macrobiota:Oecd Tg 307 May Be Adopted With Necessary Adaptations For Aerobic-Anaerobic Transformation Of Naips Or Naps In Soil. 23 Effects On Soil Microbiota And Macrobiota:Oecd Guidelines For The Testing Of Chemicals, Section 3: Test No. 318 May Be Adopted With Modifications For Naips And Naps. 24 Packaging Compatibility Data: Decision Framework ( Oecd, Env / Jm / Mono ( 2019 ) 12 ) For Inclusion Of Physico-Chemical Parameters For Exposure And Fate Assessment Of Naips. 25 Packaging Compatibility Data:Avain Dietary Toxicity ( Oecd205 ) -5 Crop Samples 26 Packaging Compatibility Data:28-Day Repeated Dose Toxicity ( Oecd407 ) -5Crop Samples 27 Packaging Compatibility Data:Leaching Study ( Oecd 312 ) -3 Type Soil And One Plant 28 Packaging Compatibility Data:Nutritional Analysis-5 Crop Samples
Basic Detail
Tender No ET-TS/Nano-Analysis TX/R D Agri /21
Bidding Type Tender
Location
City RCF TROMBAY UNIT
State Maharashtra
Key Dates
Publish Date 04 Aug 2021
Submission Date 09 Aug 2021
Open Date 09 Aug 2021
Finance
Tender Value Ref. Documents
Tender Fee Ref. Documents
EMD Ref. Documents
Exemption Not Available
Document List
5FB21F44-6919-4CD6-97CA-1B8BF63AB7A3.html
Tendernotice_1.pdf
BOQ_672297.xls

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Tender Timeline

Aug 04, 2021
11:30 IST

Tender Published

Tender notice published.

Completed
Aug 04, 2021
18:00 IST

Corrigendum-1 Issued

Clarifications on tender conditions and amendments issued.

Completed
Aug 09, 2021
18:00 IST

Corrigendum-2 Issued

Clarifications on tender conditions and amendments issued.

Completed
Aug 09, 2021
17:00 IST

Bid Submission Deadline

Online submission via eProcurement portal.

Completed
Aug 09, 2021

Bid Opening Date

Technical bids will be opened and evaluated.

Completed

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