Tenders Are Invited For Research And Experimental Development Services - Insulation And Concentration Of Staphylococcal Anatoxins From Culture Solutions. Standardization Of Developed Procedures.

Research And Experimental Development Services - Insulation And Concentration Of Staphylococcal Anatoxins From Culture Solutions. Standardization Of Developed Procedures.. The Subject Of The Order Is The Insulation And Concentration Of Staphylococcal Anatoxins From Cultivation Solutions Along With The Standardization Of Developed Procedures. As Part Of The Service, The Contracting Authority Requires The Following Partial Activities: A) The Contracting Authority Shall Supply The Culture Media Containing Anatoxins, Obtained As Hemolyzines During The Cultivation Of The Above Vaccine Bacterial Staphylococcal Tribes. Specifically, The Contractual Contract Concerns The Inactivated Alpha Hemolyzine, Beta Or Delta If It Is Contained In The Medium. We Require The Development Of Insulation Technology And Purification Of These Anatoxins From The Supplied Culture Media That Contain Them. The Developed Technology Will Be Standardized To Be Applicable In Possible Commercial Production At The Gmp Requirements. B) The Service Will Also Include The Development Of The Technology Of Centers Of Isolated And Purified, The Above, Anatoxins. The Technology Of The Concentration Of Anatoxins Will Be Standardized With The Fact That It Will Be Applicable In Possible Commercial Production At The Gmp Requirements Level. C) The Output Of The Service Will Be Documentation To A), B) And The Design Of Methodologies For Control Tests, Applicable To The Quality Of These Semi -Finished Products In Production. Another Output Of The Service Will Be The Delivery Of Samples Of Concentrated Anatoxins Obtained According To Points A), B). 10 Ml Of Concentrate With Documentation Will Be Delivered From Each Anatoxin.