Grants Notice For Blueprint Neurotherapeutics Network (Bpn): Small Molecule Drug Discovery And Development For Disorders Of The Nervous System (U44 Clinical Trial Optional

Tender Detail

72167695
PAR-24-063
Self-Funded
Grants Notice For Blueprint Neurotherapeutics Network (Bpn): Small Molecule Drug Discovery And Development For Disorders Of The Nervous System (U44 Clinical Trial Optional
NCB
Americas
Asia-Pacific Economic Cooperation, APEC,APAC ( Asia Pacific)
18-08-2024

Work Detail

Blueprint Neurotherapeutics Network (Bpn): Small Molecule Drug Discovery And Development For Disorders Of The Nervous System (U44 Clinical Trial Optional Reissue Of Par-18-541. The Blueprint Neurotherapeutics Network (Bpn) Encourages Applications From Small Businesses Seeking Support To Advance Their Small Molecule Drug Discovery And Development Projects Into The Clinic. Participants In The Bpn Are Responsible For Conducting All Studies That Involve Disease- Or Target-Specific Assays, Models, And Other Research Tools And Receive Funding For All Activities To Be Conducted In Their Own Laboratories. In Addition, Applicants Will Collaborate With Nih-Funded Consultants And Can Augment Their Project With Nih Contract Research Organizations (Cros) That Specialize In Medicinal Chemistry, Pharmacokinetics, Toxicology, Formulations Development, Chemical Synthesis Including Under Good Manufacturing Practices (Gmp), And Phase I Clinical Testing. Projects Can Enter Either At The Discovery Stage, To Optimize Promising Hit Compounds Through Medicinal Chemistry To The Development Stage, To Advance A Single Development Candidate Through Investigational New Drug (Ind)-Enabling Toxicology Studies And Phase I Clinical Testing. Alternatively, Projects Can Enter At The Development Stage And Progress In A Shorter Period To Ind Enabling Toxicology Studies And Phase I Clinical Testing. Projects That Enter At The Discovery Stage And Meet Their Milestones May Continue On Through Development. Bpn Awardee Institutions Retain Their Assignment Of Ip Rights And Gain Assignment Of Ip Rights From The Bpn Contractors (And Thereby Control The Patent Prosecution And Licensing Negotiations) For Drug Candidates Developed In This Program

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