Tenders Are Invited For Research And Development Services And Related Consultancy Services – Nanomaterial Risk Assessment: Refining And Validating Acceptable Variation In Nanoform Characterisers

Research And Development Services And Related Consultancy Services – Nanomaterial Risk Assessment: Refining And Validating Acceptable Variation In Nanoform Characterisers. The Contract Is Meant To Follow Up To On Previous Project “Nanomaterial Risk Assessment: A Regulatory Way Forward For Sameness And Grouping Approaches” Contracted In 2023. In The Previous Contract, A Framework Was Developed To Assess The Acceptable Variation Within Each Characteriser Of A Nanoform. That Project Aimed At Exploring Ways To Simplify Nanoforms Registration Process And, Ultimately, Its’ Associated Testing Burden. As An Outcome, A Series Of Binary Decision Trees And Respective Variability Threshold Were Produced, Covering Each Mandatory Characteriser. The Framework Was Developed Based On A Limited Set Of Information Covering Metallic And Carbon-Based Nanomaterials. The Present Contract Aims At Refining The Threshold Values Pre-Established And Validating It With Additional Data Sets, Covering A Wider Range Of Chemical Types. This Project’S Outcome Is Expected To Become A Basis For Echa To Develop New Guidance For Registrants Of Nanoforms Of A Substance.