Request For Quotation Purchase Of Medical Products In Accordance With Technical Specifications (Through Paid Services)

Karyomax Colcemid Solution In Pbs, 10 Ml. Technical Characteristics: The Reagent Must Be A Ready-To-Use Liquid Solution Of N-Desacetyl-N-Methylocolchicine (Colcemid), Intended To Arrest Mammalian Cells In Metaphase Of The Cell Cycle For The Purpose Of Subsequent Chromosome Separation And Analysis. The Drug Must Be Used In Cytogenetic Studies And Must Also Be Suitable For Use In In Vitro Diagnostic Procedures, Clinical And Translational Studies. The Active Substance Must Be Dissolved In Phosphate-Buffered Saline (Pbs). The Concentration Of Colcemid™ Must Be At Least 10 Μg/Ml. The Mechanism Of Action Of The Reagent Should Be To Inhibit The Formation Of The Spindle During Mitosis, Causing Metaphase Arrest Of The Cell Cycle. The Drug Should Have A Mechanism Of Action Similar To Colchicine, And Should Be Characterized By Lower Toxicity To Mammalian Cells. The Reagent Must Be In Liquid Form And Must Be Sterile Filtered. The Ph Value Of The Solution Must Be In The Range Of Not Less Than 6.0 And Not More Than 8.0. The Volume Of The Primary Packaging Must Be At Least 10 Ml. The Drug Must Belong To The Karyomax Line And Must Be Classified As A Reagent For Chromosome Analysis. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 4919.2-2016, Medium For Cell Karyotyping Pb-Max, 100 Ml. Technical Characteristics: The Medium Is A Fully Enriched Nutrient Medium Intended For Short-Term Cultivation Of Peripheral Blood Lymphocytes For The Purpose Of Cytogenetic Studies And In Vitro Diagnostic Procedures. The Environment Is Designed To Provide Consistent And Reproducible Results For Karyotype Analysis. The Product Is Supplied In A Ready-To-Use Format As A Frozen 1X Medium And Does Not Require The Addition Of Any Additional Components. Once Thawed, The Media Can Be Stored At 2 To 8°C For Up To 14 Days Without Loss Of Functionality. Each Production Batch Undergoes Mandatory Quality And Performance Testing In A Certified Reference Cytogenetic Laboratory. As Part Of The Control, Peripheral Blood Lymphocytes From A Healthy Adult Donor Are Cultured For 72 Hours, After Which Mitotic Index And Chromosomal Band Resolution Are Assessed. Additionally, Each Batch Is Tested For Sterility, Ph Level, Osmolality And The Absence Of Mycoplasma, Which Ensures A High Level Of Product Reliability And Safety. The Medium Is Based On The Classic Optimized Formula Rpmi 1640 And Contains Fetal Bovine Serum (Fbs), L-Glutamine And Phytohemagglutinin (Pha). The Formula Was Developed In Accordance With The Recommendations And Protocols Set Forth In The Association Of Cytogenetic Technologists Laboratory Manual For Culturing Peripheral Blood Lymphocytes For Cytogenetic Analysis. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 29112-91, Karyomax™ Giemsa Dye Solution, 100 Ml. Technical Characteristics: The Solution Is Intended For G-Band Staining Of Chromosomes As Part Of Cytogenetic Analysis And Should Contain 6.0 G Azur Ii Eosin And 1.6 G Azur Ii Per Liter In A Mixture Of Glycerol And Methanol. The Product Must Be Used For Use With Mammalian Cells. The Solution Must Be Sterile Filtered, Supplied In Liquid Form, Package Volume - 100 Ml, Shelf Life - 24 Months From The Date Of Production. Storage Conditions Should Be In The Range Of 15–30 °C With Mandatory Protection From Light. Transportation Conditions: At Room Temperature. At The Time Of Delivery, The Supplier Undertakes To Provide The Original Authorized Letter Or Power Of Attorney From The Manufacturer. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 4919.2-2016, Hepes Reagent (1 M), 100 Ml. Technical Characteristics: The Reagent (N-2-Hydroxyethylpiperazine-N-2-Ethanesulfonic Acid) Is A Zwitterionic Organic Chemical Buffer Agent Commonly Used In Cell Culture Media. The Buffer Volume Should Be No More Than 100 Ml. The Form Of The Buffer Should Be: Liquid; The Buffer Must Have: Negative Bacterial Test; Diploid Height Not Less Than 0.70 Not More Than 1.40; Negative Test For Fungi; Osmolality Should Be No Less Than 1450 And No More Than 1800 Mosm/Kg; The Ph Must Be No Less Than 7.00 And No More Than 7.50. The Supplier Undertakes To Provide The Original Authorized Letter Or Power Of Attorney From The Manufacturer. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 4212-2016, Technical Characteristics: The Phenol Red Solution Is Intended For The Dissociation Of Mammalian Cells In Vitro And Must Contain Trypsin, Edta And Phenol Red. Trypsin Must Be Obtained From Trypsin Powder And Is An Irradiated Mixture Of Animal Proteases Obtained From The Pancreas Of A Pig. The Solution Must Have Sufficient Proteolytic Activity For Cell Dissociation, Routine Passage Of Cell Cultures And Dissociation Of Primary Tissues, With Trypsin Concentration Adjusted Depending On The Cell Type And Experimental Conditions. The Solution Must Be Modified By Adding Edta And Phenol Red. The Product Must Undergo Multi-Stage Quality Control, Including Testing For Ph, Osmolality, Sterility And Functional Activity. The Phenol Red Solution Must Be Manufactured In Accordance With Cgmp Requirements Certified To Iso 13485. The Concentration Of The Solution Should Be 1X, Osmolality 270–320 Mosm/Kg, Ph 7.2–8.0. The Solution Must Be Sterile Filtered, In The Form Of A Liquid Reagent, Package Volume - 100 Ml. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 4919.2-2016, Nunc™ Scrapers For 23 Cm Cages, 250 Pcs/Pack. Technical Characteristics: The Scraper For Removing Adhesive Cells Is Designed For Mechanical Collection Of Cells From The Surface Of Culture Flasks And Other Culture Dishes. The Product Is Equipped With A Flexible, Adjustable Blade That Ensures Effective And Gentle Separation Of The Cell Monolayer Without Damaging The Surface Of The Vessel. The Scraper Is Compatible With Culture Flasks With A Growth Area From 25 To 80 Cm². The Handle Is Made Of Polystyrene And Has A Length Of 23 Cm, Which Makes It Easy To Work With Various Types Of Culture Dishes. The Blade Size Is 17.5 × 7.5 Mm. The Product Is Sterile, Pyrogen-Free, Supplied In Individual Packaging And Intended For Single Use. Used In Cell Biology, Biotechnology, Molecular Biology Laboratories And Research Centers For Cell Culture And Collection. The Package Contains 250 Scrapers. Compliance With The International Standard Iso 10993. The Supplier Undertakes To Provide The Original Authorized Letter Or Power Of Attorney From The Manufacturer. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense., Medium For Culturing Amniotic Fluid Cells 100 Ml Amniomax - Ii Complete Medium 100 Ml. Amniotic Fluid Cell Culture Medium Is A Complete Medium Designed For The Short-Term Culture Of Human Amniotic Fluid Cells For Cytogenetic Studies And In Vitro Diagnostic Procedures. The Medium Should Contain Fetal Bovine Serum (Fbs), Gentamicin, And L-Glutamine To Maximize Cell Attachment And Growth. This Optimized Medium Also Has An Improved Buffer System That Provides Greater Ph Stability During Culture Manipulations. Volume Not Less Than 100 Ml. The Supplier Undertakes To Provide The Original Authorized Letter Or Power Of Attorney From The Manufacturer. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 29112-91, Dulbeccos Phosphate-Buffered Saline (Dpbs), Calcium-Free, Magnesium-Free, 500 Ml. Technical Specifications: Dulbeccos Phosphate-Buffered Saline Solution Is Intended For Use In Cell Culture And Should Be Used For Washing Cells Before Dissociation, Transporting Cells Or Tissue Samples, Diluting Cells For Counting, And Preparing Reagents. The Product Must Be Free Of Calcium, Magnesium And Phenol Red. The Concentration Of The Solution Should Be 1X, The Osmolality Should Be No Less Than 270 Mosm/Kg And No More Than 300 Mosm/Kg, And The Ph Of The Solution Should Be In The Range Of 7.0 -7.3. The Product Must Be Sterile Filtered And Supplied In Liquid Form, Packaging Volume - 500 Ml. The Supplier Provides Documents Confirming The Compliance Of The Supplied Goods With The Requirements Established By Technical Regulations, Provisions Of Standards Or Other Documents In Accordance With The Legislation Of The Republic Of Kazakhstan, Including A Registration Certificate In The Ministry Of Health Of The Republic Of Kazakhstan, Or A Refusal Letter From The Authorized Body. Delivery Is Carried Out By The Supplier At Its Own Expense. Gost 4919.2-2016