Tenders Are Invited For Laboratory, Optical And Precision Equipments (Excl. Glasses) – Single-Cell Multi-Omics Analysetoestel

Laboratory, Optical And Precision Equipments (Excl. Glasses) – Single-Cell Multi-Omics Analysetoestel. Object Of The Contract: This Contract Concerns The Purchase, Supply And Installation Of An Advanced Single-Cell Multi-Omics Analysis Device, Including All Necessary Accessories And Services, For Use In Immunological And Molecular Research. This Is A Solution That Allows The Collection Of Transcriptomic, Proteomic And Epigenetic Information At Cell Level In One Integrated Workflow. Explanation: The Aim Of This Assignment Is To Provide Innovative Technology That Makes It Possible To Study Complex Biological Systems At Single Cell Level. This Is Essential For Research Into Immunological Mechanisms, Vaccine Responses And Personalized Medicine. The Chosen Solution Must: • Support Single-Cell Multi-Omics Analyzes (Rna-Seq, Atac-Seq, Cite-Seq, Tcr/Bcr Repertoire). Includes True Multi-Omics Integration (Rna-Seq, Atac-Seq, Cite-Seq, Tcr/Bcr Repertoire) In One Workflow (Multiplexing And Protein Profiling). • Provide Efficient And Reproducible Workflows, With Quality Control At Every Critical Point To Avoid Waste Of Valuable Sequencing. • Ensure Flexibility In Throughput (From Several Hundred To Hundreds Of Thousands Of Cells Per Run), With The Option Of Partial Use Of Cartridges To Minimize Batch Effects. Includes Lower Costs Per Cell And Better Read Utilization, Crucial For Large-Scale Studies • Compatibility With Multiplexing And Immunophenotyping (E.G. Via Oligo-Conjugated Antibodies) For In-Depth Characterization Of Cellular Subsets. • Support For Fragile Or Rare Cells By Using Soft Microwell Technology Instead Of Microfluidic Droplets, Reducing Risk Of Sample Loss Or Damage. • Integrated Quality Control Via A Scanner That Counts Cells, Determines Viability And Calculates Multiplet Ratios Before Sequencing, Enabling Real-Time Decisions. The Scope Of The Assignment Includes: • Purchase, Delivery And Installation Of The Device And All Necessary Components. • Training For Users And Technical Staff. • Device-Related Reagents And Consumables (E.G. Cartridges, Wta, Atac, Tcr/Bcr And Multiplexing Kits). • Delivery, Installation, Validation, Inspection And Commissioning In Accordance With Applicable Standards. • Warranty Conditions: The Device Must Be Supplied With A Minimum Of 1 Year Standard Warranty On Parts And Labor. An Extension To A 2-Year Warranty Is Desirable And Will Be Positively Assessed In The Award Criteria. • Optional Maintenance Contract From Expiration Of The Warranty. • Provision For Future Innovation And Expansion: The System Must Be Compatible With New Analytical Methods And Kits Coming Onto The Market In The Coming Years, So That The Investment Remains Sustainable And Can Grow With Technological Developments (E.G. Integration Of New Multi-Omics Workflows, Improved Multiplexing, Or Software

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