Medical Equipments – Automated Adamts-13 Special Coagulation Analytics For Hus Diagnostic Center. The Hus Group Requests Tenders For The Following Entity: The Object Of The Procurement Is The Analytics For Measuring The Enzymatic Activity Of Adamts-13 As A Random Access-Based Definition. Adamts-13 (A Disintegrin And Metalloproteinase With A Thrombospondin Type 1 Motif, Member 13) Cleaves The Multimer Structures Of The Von Willebrand Factor. In Thrombotic Thrombocytopenic Purpura (Ttp), Adamts-13 Activity Has Declined, Leading To The Formation Of Extra-Large Vwf Multimer Structures And To Thrombosis Complications. The Patients Are Often Critically Ill And Low Adamts-13 Activity Confirms The Diagnosis. The Fastest Possible Diagnostics Is Therefore Needed. The Random Access Method Enables Faster Response Times, Which Is A Significant Advantage Especially In The Clinical Use Of Adamts-13 Measuring. An Automated System Also Reduces The Workload Involved In These Measurements. The Products Are Described In More Detail In In Appendix 1 To The Invitation To Tender (Price And Product Form). This Is A Total Procurement, I.E. The Procurement Is Not Divided Into Lots Because The Procurement Seeks A Comprehensive Solution For Adamts-13 Coagulation Analytics, Including The Device (One Analyzer) And Its Maintenance And Supplies. The Reagents And Other Supplies Required For The Device Shall Be Located In The Consignment Stock Established By The Selected Tenderer In The Client’S Service Location. The Procurement Also Includes An Option For The Additional Procurement Of One (1) Equipment Including Its Maintenance, For Example, If The Production Amounts Increase During The Contract Period. These Are The Client’S (Hus) Options, I.E., The Decision On Using The Options Is Made By The Procurement Entity. The Studies Mentioned In This Call For Tenders Will Be Carried Out By The Hus Group. The Analytics Will Be Performed In The Coagulation Laboratory Of The Automated Laboratory In The Huslab Building. The Adamts-13 Samples Usually Arrive One By One And Are Analyzed On A Daily Basis. The Controls At Both Levels Are Usually Analyzed Once On The Days On Which The Sample Is Analyzed. Therefore, In Practice, The Definition Of One Sample Always Uses The Reagent To The Amount Required For The Sample And Two Controls. In 2024, A Total Of 370 P -Adam13 Studies Were Carried Out At Hus Diagnostic Center. The Client Already Uses The Existing Equipment It Has Purchased (Acustar Bio-Flash Equipment, 2 Pcs) To Perform The Studies. If The Offered Tests Can Be Performed Using The Client’S Own Existing Equipment, The Use Of This Equipment Can Be Continued Until The End Of Its Life Cycle. In This Case, An Order For The New Device May Not Necessarily Be Placed During The Contract Period Concluded On The Basis Of This Competitive Tendering Process. The Decision On Placing The Order Is Made By The Client. If The Client Does Not Have Existing Equipment Of Its Own For Performing The Offered Tests, The Order For A New Device Will Be Made After The Procurement Decision. After Havi
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