Tender Result - Tender For Supply Of Molecular Diagnostic Kit- 1 EGFR Mutation Analysis Kit (Performance certificate for timely supply)1) IVD Certified2) Should detect all clinically relavant mutation in Exon 18,19,20 and 213) Compactable to Real Time PCR-ABI 7500 DX 4)Sensitivity and specificity should be mentioned 5) Kit should work with FFPE samples6) If requested on site demo with 5 sample should be performed7) List of mutations which can be detected should be mention8) User list of 3 hospital or medical institute should be provided9) On site technical team support should be given on request 2 JAK 2 Kit 1. IVD Certified 2. Should detect V617F and exon 12 mutation3. Compactable to Real Time PCR-ABI 7500 DX4.Sensitivity and specificity should be mentioned 5. Kit should work with blood DNA6. If requested on site demo with 5 sample should be performed 7. List of mutations which can be detected should be mention 8. User list of 3 hospital or medical institute should be provided 9. On site technical team support should be given on request 3 FLT3ITD Kit1. IVD/CECertified 2. Should detect internal tandem duplication(ITD) mutations and tyrosine kinase domain (TKD) mutations D835 & E8363. Compactable to Real Time PCR-ABI 7500 DX or gel based 4.Sensitivity and specificity should be mentioned5. Kit should work with blood DNA6. If requested on site demo with 5 sample should be performed 7. List of mutations which can be detected should be mention8. User list of 3 hospital or medical institute should be provided9. On site technical team support should be given on request 4 BCR-ABLQuantization kit1. IVD Certified2. Should detect in IS scale3. Compactable to Real Time PCR-ABI 7500 DX4. or more point standard for Abl and BCR-Abl should be provided 5. Sensitivity and specificity should be mentioned 6. Reference RNA should beprovided (for 15 runs)- May be supplied in batches.7. If requested on site demo with 5 sample should be performed 8. List of fussion which can be detected should be mention(fussion)9. User list of 3 hospital or medical institute should be provided 10. On site technical team support should be given on request 5 PML-RAra Kit 1.Should detect BCR1,BCR2 and BCR3 Type2. Compactable to Real Time PCR-ABI 7500 DX or gel based.4. Should perform qualitative detection5. Sensitivity and specificity should be mentioned 6. If requested on site demo with 5 sample should be performed 7. User list of 3 hospital or medical institute should be provided 8. On site technical team support should be given on request 6 Leukemia Panel forfollowing(PCR Based)1. Should detected following- AML1 - ETO -CBFB – MYH -MLL – AF4 - TEL- AML1 - E2A – PBX- PML – RARa- Should compatible for 7500DX or gel based 7 MPN Panel Should detect following - BCR-ABL - CALR – Type I & Type II -MPL Mutation – 515 & 505 -JAK2 V617 F -Should compatible for 7500DX or gel based 8 IDH I & IDH II Should detect following- R132H - R132C For IDH I- R100Q - R132Xa- R172K- R140XIDH II- R172X- Should compatible for 7500DX or gel based 9 KRAS & NRASPANELShould detectmutation in following codones Codon 12 13, 61, 117, 143 ®Should compatible for 7500DX or gel based 10 B-RAF Analysis Codon 600Should compatible for 7500DX or gel based 11 AML Panel - CBFB-MYH11 -BCR-Abl -PML-RARa -AML-ETO-c-KIT -NPM1 -FLT3 KTD -FLT-ITD-Or more markers -Should compatible for 7500DX or gel based 12 ALLPanel- E2A-PBX1-TEL-AML1 -MLL-AF4- MLL-ENL-BCR-Abl-Or more markersShould compatible for 7500DX or gel based 13 Immunoglobin (IgH) rearrangement analysis kit Should compatible for 7500DX or gel based 14 Thrombosis SNP Panel Assay -Factor II - G20210-A Factor V - H1299R -Factor V - R506Q-Factor V - Y1702C- MTHFR - A1298C - MTHFR - C677T Should compatible for 7500DX or gel based 15 DPYD gene polymorphisms DPYD*2A (IVS14+1G>A, c.1905+1G>A, rs3918290),DPYD*13 (c.1679T>G, rs55886062), DPYD D949V (c.2846A>T, rs67376798) and DPYD IVS10 (c.1129–5923C>G, rs75017182), Should compatible for 7500DX or gel based 16 UGT1A1 gene polymorphisms UGT1A1*1 (TA)6, UGT1A1*28 (TA)7, UGT1A1*36(TA)5 and UGT1A1*37 (TA)8, Should compatible for 7500DX or gel based

7650255

Malabar Cancer Centre

Tender For Supply Of Molecular Diagnostic Kit- 1 EGFR Mutation Analysis Kit (Performance certificate for timely supply)1) IVD Certified2) Should detect all clinically relavant mutation in Exon 18,19,20 and 213) Compactable to Real Time PCR-ABI 7500 DX 4)Sensitivity and specificity should be mentioned 5) Kit should work with FFPE samples6) If requested on site demo with 5 sample should be performed7) List of mutations which can be detected should be mention8) User list of 3 hospital or medical institute should be provided9) On site technical team support should be given on request 2 JAK 2 Kit 1. IVD Certified 2. Should detect V617F and exon 12 mutation3. Compactable to Real Time PCR-ABI 7500 DX4.Sensitivity and specificity should be mentioned 5. Kit should work with blood DNA6. If requested on site demo with 5 sample should be performed 7. List of mutations which can be detected should be mention 8. User list of 3 hospital or medical institute should be provided 9. On site technical team support should be given on request 3 FLT3ITD Kit1. IVD/CECertified 2. Should detect internal tandem duplication(ITD) mutations and tyrosine kinase domain (TKD) mutations D835 & E8363. Compactable to Real Time PCR-ABI 7500 DX or gel based 4.Sensitivity and specificity should be mentioned5. Kit should work with blood DNA6. If requested on site demo with 5 sample should be performed 7. List of mutations which can be detected should be mention8. User list of 3 hospital or medical institute should be provided9. On site technical team support should be given on request 4 BCR-ABLQuantization kit1. IVD Certified2. Should detect in IS scale3. Compactable to Real Time PCR-ABI 7500 DX4. or more point standard for Abl and BCR-Abl should be provided 5. Sensitivity and specificity should be mentioned 6. Reference RNA should beprovided (for 15 runs)- May be supplied in batches.7. If requested on site demo with 5 sample should be performed 8. List of fussion which can be detected should be mention(fussion)9. User list of 3 hospital or medical institute should be provided 10. On site technical team support should be given on request 5 PML-RAra Kit 1.Should detect BCR1,BCR2 and BCR3 Type2. Compactable to Real Time PCR-ABI 7500 DX or gel based.4. Should perform qualitative detection5. Sensitivity and specificity should be mentioned 6. If requested on site demo with 5 sample should be performed 7. User list of 3 hospital or medical institute should be provided 8. On site technical team support should be given on request 6 Leukemia Panel forfollowing(PCR Based)1. Should detected following- AML1 - ETO -CBFB – MYH -MLL – AF4 - TEL- AML1 - E2A – PBX- PML – RARa- Should compatible for 7500DX or gel based 7 MPN Panel Should detect following - BCR-ABL - CALR – Type I & Type II -MPL Mutation – 515 & 505 -JAK2 V617 F -Should compatible for 7500DX or gel based 8 IDH I & IDH II Should detect following- R132H - R132C For IDH I- R100Q - R132Xa- R172K- R140XIDH II- R172X- Should compatible for 7500DX or gel based 9 KRAS & NRASPANELShould detectmutation in following codones Codon 12 13, 61, 117, 143 ®Should compatible for 7500DX or gel based 10 B-RAF Analysis Codon 600Should compatible for 7500DX or gel based 11 AML Panel - CBFB-MYH11 -BCR-Abl -PML-RARa -AML-ETO-c-KIT -NPM1 -FLT3 KTD -FLT-ITD-Or more markers -Should compatible for 7500DX or gel based 12 ALLPanel- E2A-PBX1-TEL-AML1 -MLL-AF4- MLL-ENL-BCR-Abl-Or more markersShould compatible for 7500DX or gel based 13 Immunoglobin (IgH) rearrangement analysis kit Should compatible for 7500DX or gel based 14 Thrombosis SNP Panel Assay -Factor II - G20210-A Factor V - H1299R -Factor V - R506Q-Factor V - Y1702C- MTHFR - A1298C - MTHFR - C677T Should compatible for 7500DX or gel based 15 DPYD gene polymorphisms DPYD*2A (IVS14+1G>A, c.1905+1G>A, rs3918290),DPYD*13 (c.1679T>G, rs55886062), DPYD D949V (c.2846A>T, rs67376798) and DPYD IVS10 (c.1129–5923C>G, rs75017182), Should compatible for 7500DX or gel based 16 UGT1A1 gene polymorphisms UGT1A1*1 (TA)6, UGT1A1*28 (TA)7, UGT1A1*36(TA)5 and UGT1A1*37 (TA)8, Should compatible for 7500DX or gel based

thalassery

Kerala

INR 2.71 Crore /-

02-02-2024