Rna Probes

Rna Probes Hhs Nih Nida Ag Css 75N95021q00047 Introduction This Is A Combined Synopsis Solicitation For Commercial Items Prepared In Accordance With The Format In Subpart 12 6 As Supplemented With Additional Information Included In This Notice This Announcement Constitutes The Only Solicitation Proposals Are Being Requested And A Written Solicitation Will Not Be Issued The Solicitation Number Is Hhs Nih Nida Ag Css 75N95021q00047 And The Solicitation Is Issued As A Request For Quotation Rfq Acquisition Authority This Acquisition Is For A Commercial Item Or Service And Is Conducted Under The Authority Of The Federal Acquisition Regulation Far Part 13 Simplified Acquisition Procedures Far Subpart 13 5 Simplified Procedures For Certain Commercial Items And Far Part 12 Acquisition Of Commercial Items And Is Not Expected To Exceed The Simplified Acquisition Threshold The Solicitation Document And Incorporated Provisions And Clauses Are Those In Effect Through Federal Acquisition Circular 2021 04 Dated January 19 2021 North American Industry Classification System Naics Code The Intended Procurement Is Classified Under Naics Code 325412 Pharmaceutical Preparation Manufacturing And The Small Business Size Standard 1250 Employees Description Of Requirement Background A Parkinson S Disease Pd Mouse Model Of Mutant And Wildtype Control Leucin Rich Repeat Kinase Lrrk2 Have Been Striatally Injected With Inflammatory Agent Lipopolysaccharide Lps And The Brain Regions Were Single Cell Rna Sequenced In Order To Compare Cell Type Specific Differences In Inflammatory Responses Which Are Suggested To Be Important Contributors To Many Neurodegenerative Disorders We Will Use The Rna Scope Hiplex Assay To Validate The List Of Differentially Expressed Genes That Was Obtained From The Single Cell Rna Sequencing This Project Will Expand Our Knowledge Of Cell Type Specific Immune Responses In Pd And Will Represent The First Study On The Inflammatory Response Of Mutated Pd Gene Lrrk2 Within Specific Brain Areas Purpose And Objectives The Purpose Of This Acquisition Is To Procure Rnascope Hiplex Assay To Analyze Differentially Expressed Genes Scope Of Work The Contractor Shall Provide The Government With Rna Probes Compatible With Rnascope Hybez Instrumentation 78 Unique Rna Probes And 1 Controls And Software Package Anticipated Period Of Performance 30 Days After Receipt Order Place Of Performance 35 Convent Drive Bethesda Md 20892 Attachments Purchase Attachment 1 Responses Must Also Include A Completed 52 204 24 Representation Regarding Certain Telecommunications And Video Surveillance Services Or Equipment Oct 2020 Attachment 2 52 204 26 Covered Telecommunications Equipment Or Services Representation Oct 2020 Attachment 3 Contract Type The Government Intends To Issue A Firm Fixed Price Commercial Items Purchase Order For This Requirement Invoicing Shall Be On A Net30 Basis And Payment Shall Be Made Via Electronic Funds Transfer Eft There Are No Additional Contract Requirement S Or Terms And Conditions Applicable To This Acquisition The Defense Priorities And Allocations System Dpas Are Not Applicable To This Requirement Applicable Clauses And Provisions The Following Far Provisions Shall Apply To This Solicitation 52 212 1 Instructions To Offerors Commercial Items 52 212 2 Offerors Must Include A Completed Copy Of The Provision At 52 212 3 Offeror Representations And Certifications Commercial Items With Their Offer The Clause At Far 52 204 24 Representation Regarding Certain Telecommunications And Video Surveillance Services Or Equipment Applies The Clause At Far 52 204 25 Prohibition On Contracting For Certain Telecommunications And Video Surveillance Services Or Equipment Applies The Clause At 52 212 4 Contract Terms And Conditions

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